Supporting discoveries since 1987


The revised American Joint Committee on Cancer (AJCC) Cancer Staging Manual1 was recently released with a new staging system for all cancer cases diagnosed on or after January 1, 2018.  The 8th edition of the Cancer Staging Manual represents an important step in refining the anatomic staging system traditionally based on primary tumor extent and nodal and distant metastasis (TNM) by including non-anatomic factors in prognostic groupings.  While the TNM components remain purely anatomic, many of the staging algorithms in the 8th edition of the Cancer Staging Manual incorporate molecular and serologic factors into new staging systems designed to reflect the current state of medical knowledge and the natural history and prognosis of cancers.  Some of the noteworthy advances in this edition include:

CAPAJCCcancer stagingcancer protocolsAmerican Joint Committee on CancerCollege of American PathologistsHPV statusTNM staging